Value of procalcitonin and presepsin in the diagnosis and severity stratification of sepsis and septic shock

doi:10.5847/wjem.j.1920-8642.2024.028

World Journal of Emergency Medicine ›› 2024, Vol. 15 ›› Issue (2): 135-138.doi: 10.5847/wjem.j.1920-8642.2024.028

Special Issue: Sepsis

• Research Letter • Previous Articles Next Articles

Value of procalcitonin and presepsin in the diagnosis and severity stratification of sepsis and septic shock Open Access

Enfeng Ren¹, Hongli Xiao¹, Guoxing Wang¹, Yongzhen Zhao², Han Yu², Chunsheng Li¹()

¹Department of Emergency Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
²Department of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100050, China

Received:2023-06-06 Accepted:2023-10-26 Online:2024-03-11 Published:2024-03-01
Contact: Chunsheng Li, Email: lcscyyy@163.com

Abstract

Enfeng Ren, Hongli Xiao, Guoxing Wang, Yongzhen Zhao, Han Yu, Chunsheng Li. Value of procalcitonin and presepsin in the diagnosis and severity stratification of sepsis and septic shock[J]. World Journal of Emergency Medicine, 2024, 15(2): 135-138.

Figures/Tables 3

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References 15

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Variables	Total (n=2,255)	Sepsis (n=1,970)	Septic shock (n=285)	P-value
Age, years	72.0 (60.0-80.0)	72.0 (60.0-80.0)	72.0 (67.0-79.0)	0.445
Male	1,338 (59.3)	1,183 (60.1)	155 (54.4)	0.079
Chronic heart disease	1-069 (47.4)	905 (45.9)	164 (57.5)	<0.001
COPD	482 (21.4)	432 (21.9)	27 (17.4)	0.107
CKD	158 (7.0)	144 (7.3)	14 (4.9)	0.175
CRP, mg/L	66.0 (50.0-82.0)	67.0 (53.0-82.0)	61.0 (35.0-87.0)	0.026
PCT, µg/L	2.0 (0.0-8.5)	2.0 (0.0-7.0)	11.0 (2.0-25.0)	<0.001
Presepsin, pg/mL	1,119.0 (664.5-1-817.0)	1,070.0 (646.0-1,710.5)	1,841.0 (870.0-3,124.0)	<0.001
PaO₂/FiO₂, mmHg	258.0 (204.0-307.0)	259.0 (208.0-306.0)	243.0 (179.0-316.0)	0.038
Lactate, mmol/L	2.0 (1.0-3.0)	2.0 (1.0-3.0)	3.0 (2.0-5.0)	<0.001
ISTH	2.0 (1.0-2.0)	2.0 (1.0-2.0)	2.0 (1.0-2.0)	0.674
APACHE II	16.0 (10.0-22.0)	15.0 (10.0-21.0)	23.0 (16.0-29.0)	<0.001
SOFA	5.0 (3.0-9.0)	4.0 (3.0-8.0)	13.0 (8.0-18.0)	<0.001
MEDS	11.0 (8.0-16.0)	11.0 (8.0-14.0)	18.0 (13.0-21.0)	<0.001
SAPS II	35.0 (28.0-43.0)	33.0 (27.0-41.0)	49.0 (40.0-59.0)	<0.001
ARDS	1,801 (79.9)	1,590 (80.7)	211 (74.0)	<0.001
AKI	952 (42.2)	736 (37.4)	216 (75.8)	<0.001
Hospitalization cost, RMB yuan	63,880.0 (38,216.5-99,073.0)	61,674.0 (36,979.0-97,029.0)	80,104.0 (49,635.0-11,2308.0)	<0.001
28-day mortality	757 (33.6)	589 (29.9)	168 (58.9)	<0.001

Value of procalcitonin and presepsin in the diagnosis and severity stratification of sepsis and septic shock Open Access

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