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World Journal of Emergency Medicine ›› 2015, Vol. 6 ›› Issue (1): 23-28.doi: 10.5847/wjem.j.1920-8642.2015.01.004

• Original Articles • Previous Articles     Next Articles

Embryonic natural orifice transluminal endoscopic surgery in the treatment of severe acute pancreatitis complicated by abdominal compartment syndrome

Hui-ming Zhu(), Shao-qing Guo, Xiu-min Liao, Li Zhang, Li Cai   

  1. Department of Gastroenterology, Affiliated Donghua Hospital of Sun Yat-sen University, Dongguan 523110, Guangdong Province, China
  • Received:2014-08-10 Accepted:2015-01-15 Online:2015-03-15 Published:2015-03-15
  • Contact: Hui-ming Zhu


BACKGROUND: The study aimed to estimate the value of embryonal natural orifice transluminal endoscopic surgery (ENOTES) in treating severe acute pancreatitis (SAP) complicated with abdominal compartment syndrome (ACS).
METHODS: The patients, who were randomized into an ENOTES group and an operative group, underwent ENOTES and laparotomy, respectively. The results and complications of the two groups were compared.
RESULTS: Enterocinesia was observed earlier in the ENOTES group than in the operative group. Acute Physiology and Chronic Health Evaluation II (APACHE II) score of patients in the ENOTES group was lower than that of the operative group on the 1st, 3rd and 5th post-operative day (P<0.05). The cure rate was 96.87% in the ENOTES group, which was statistically different from 78.12% in the operative group (P<0.05). There were significant differences in complications and mortality between the two groups (P<0.01).
CONCLUSION: Compared with surgical decompression, ENOTES associated with flexible endoscope therapy is an effective and minimal invasive procedure with less complications.

Key words: Embryonal natural orifice transluminal endoscopic surgery, Flexible endoscope, Peritoneal lavage, Peritoneal dialysis, Severe acute pancreatitis, Abdominal compartment syndrome