World Journal of Emergency Medicine ›› 2012, Vol. 3 ›› Issue (2): 128-134.doi: 10.5847/wjem.j.issn.1920-8642.2012.02.009
• Original Articles • Previous Articles Next Articles
Cheng Zhang, Guang-rong Gao, Hui-yong Jiang, Chen-guang Lv, Bao-lei Zhang, Ming-shuang Xie, Zhi-li Zhang, Li Yu, Xue-feng Zhang()
Received:
2011-11-19
Accepted:
2012-03-20
Online:
2012-06-15
Published:
2012-06-15
Contact:
Xue-feng Zhang
E-mail:cz1791@126.com
Cheng Zhang, Guang-rong Gao, Hui-yong Jiang, Chen-guang Lv, Bao-lei Zhang, Ming-shuang Xie, Zhi-li Zhang, Li Yu, Xue-feng Zhang. Effects of environmental hypothermia on hemodynamics and oxygen dynamics in a conscious swine model of hemorrhagic shock[J]. World Journal of Emergency Medicine, 2012, 3(2): 128-134.
Add to citation manager EndNote|Ris|BibTeX
URL: http://wjem.com.cn//EN/10.5847/wjem.j.issn.1920-8642.2012.02.009
Table 1
Effect of environmental temperature on PO2, PCO2, HR, DO2I and VO2I during HS (mean±SD)
Variables | BL | HST 30min | HST 1h | HST 2h | HST 3h | HST 4h |
---|---|---|---|---|---|---|
PO2 (mmHg) | ||||||
Group A | 102±15 | 97±12 | 96±18 | 95±17 | 99±21 | 95±14 |
Group B | 99±8 | 100±11 | 94±19 | 92±13 | 98±13 | 93±16 |
PCO2 (mmHg) | ||||||
Group A | 38±4.1 | 24±4.3 | 29±4.2 | 34±2.9 | 35±3.8 | 34±4.2 |
Group B | 39±4.7 | 28±7.1 | 32±6.1 | 34±7.7 | 34±7.2 | 36±3.7 |
HR (beats/min) | ||||||
Group A | 99±23 | 166±15 | 160±26 | 146±31 | 125±33 | 130±26 |
Group B | 103±19 | 174±39 | 161±34 | 155±17 | 146±27 | 155±15 |
DO2I (mL/min?m2) | ||||||
Group A | 834±65 | 221±64 | 284±85 | 283±66 | 306±75 | 288±77 |
Group B | 783±74 | 197±54 | 217±95 | 236±69 | 242±52 | 206±51 |
VO2I (mL/min?m2) | ||||||
Group A | 347±76 | 160±37 | 185±39 | 176±36 | 170±44 | 167±56 |
Group B | 299±71 | 146±32 | 137±27 | 172±51 | 186±33 | 152±36 |
1 |
Shafi S, Elliott AC, Gentilello L. Is hypothermia simply a marker of shock and injury severity or an independent risk factor for mortality in trauma patients? Analysis of a large national trauma registry. J Trauma 2005; 59:1081-1085.
doi: 10.1097/01.ta.0000188647.03665.fd pmid: 16385283 |
2 |
Mizushima Y, Wang P, Cioffi WG, Bland KI, Chaudry IH. Restoration of body temperature to normothermia during resuscitation following trauma-hemorrhage improves the depressed cardiovascular and hepatocellular functions. Arch Surg 2000; 135:175-181.
doi: 10.1001/archsurg.135.2.175 pmid: 10668877 |
3 |
Mizushima Y, Wang P, Cioffi WG, Bland KI, Chaudry IH. Should normothermia be restored and maintained during resuscitation after trauma and hemorrhage? J Trauma 2000; 48:58-65.
doi: 10.1097/00005373-200001000-00010 pmid: 10647566 |
4 |
Morel N, Morel O, Chimot L, Lortet V, Julliac B, Lelias A. et al. Acute traumatic haemorrhagic shock and transfusion: what's new in 2009? Ann Fr Anesth Reanim 2009; 28:222-230.
doi: 10.1016/j.annfar.2008.12.023 pmid: 19278810 |
5 |
Duchesne JC, McSwain NE Jr, Cotton BA, Hunt JP, Dellavolpe J, Lafaro K. et al. Damage control resuscitation: the new face of damage control. J Trauma 2010; 69:976-690.
doi: 10.1097/TA.0b013e3181f2abc9 pmid: 20938283 |
6 | US Government Printing Office. Emergency War Surgery. Third United States Revision. Washington,DC: US Government Printing Office; 2004. |
7 |
George ME, Mulier KE, Beilman GJ. Hypothermia is associated with improved outcomes in a porcine model of hemorrhagic shock. J Trauma 2010; 68:662-668.
doi: 10.1097/TA.0b013e3181d3cbc0 pmid: 20220422 |
8 |
Wu X, Kochanek PM, Cochran K, Nozari A, Henchir J, Stezoski SW. et al. Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs. J Trauma 2005; 59:291-299
doi: 10.1097/01.ta.0000179445.76729.2c pmid: 16294067 |
9 |
Nishi K, Takasu A, Shibata M, Uchino S, Yamamoto Y, Sakamoto T. Hypothermia reduces resuscitation fluid volumes required to maintain blood pressure in a rat hemorrhagic shock model. J Trauma Acute Care Surg 2012; 72:130-135.
doi: 10.1097/TA.0b013e31821e61d8 pmid: 21768895 |
10 |
Zink BJ, Syverud SA, Dronen SC, Barsan WG, Van Ligten P, Timerding BL. The effect of ethanol on survival time in hemorrhagic shock in an unanesthetized swine model. Ann Emerg Med 1988; 17:15-19.
doi: 10.1016/s0196-0644(88)80496-7 pmid: 3337408 |
11 |
Takasu A, Ishihara S, Anada H, Sakamoto T, Okada Y. Surface cooling, which fails to reduce the core temperature rapidly, hastens death during severe hemorrhagic shock in pigs. J Trauma 2000; 48:942-947.
doi: 10.1097/00005373-200005000-00021 pmid: 10823541 |
12 |
Tsukamoto T, Pape HC. Animal models for trauma research: what are the options? Shock 2009; 31:3-10.
doi: 10.1097/SHK.0b013e31817fdabf pmid: 18636048 |
13 |
Alam HB, Chen Z, Li Y, Velmahos G, DeMoya M, Keller CE. et al. Profound hypothermia is superior to ultraprofound hypothermia in improving survival in a swine model of lethal injuries. Surgery 2006; 140:307-314.
doi: 10.1016/j.surg.2006.03.015 pmid: 16904984 |
14 |
Drabek T, Kochanek PM, Stezoski J, Wu X, Bayir H, Morhard RC. et al. Intravenous hydrogen sulfide does not induce hypothermia or improve survival from hemorrhagic shock in pigs. Shock 2011; 35:67-73.
doi: 10.1097/SHK.0b013e3181e86f49 pmid: 20523266 |
15 |
Takizawa D, Sato E, Kurosaki D, Hiraoka H, Horiuchi R, Goto F. Pharmacodynamics of propofol during hemorrhagic shock. Anesthesiology 2005; 102:1068-1069.
doi: 10.1097/00000542-200505000-00033 pmid: 15851900 |
16 |
Brezina A, Drabek T, Riha H, Schreiberova J, Hess L. The effect of medetomidine-ketamine anesthesia on hemodynamic parameters during hemorrhagic shock in minipigs. Physiol Res 2010; 59:703-710.
pmid: 20406031 |
17 |
Rhee P, Burris D, Kaufmann C, Pikoulis M, Austin B, Ling G. et al. Lactated Ringer's solution resuscitation causes neutrophil activation after hemorrhagic shock. J Trauma 1998; 44:313-319.
doi: 10.1097/00005373-199802000-00014 pmid: 9498503 |
18 | Cheng C, Matsukawa T, Sessler DI, Ozaki M, Kurz A, Merrifield B. et al. Increasing mean skin temperature linearly reduces the core-temperature thresholds for vasoconstriction and shivering in humans. Anesthesiology1995; 82:1160-1168. |
19 | Frank SM, Cattaneo CG, Wieneke-Brady MB, El-Rahmany H, Gupta N, Lima JA. et al. Threshold for adrenomedullary activation and increased cardiac work during mild core hypothermia. ClinSci(Lond) 2002; 102:119-125. |
20 | Frank SM, Higgins MS, FleisherLA, Sitzmann JV, Raff H, Breslow MJ. Adrenergic, respiratory, and cardiovascular effects of core cooling in humans. AmJPhysiol 1997; 272:R557-R562. |
21 | Taniguchi Y, Lenhardt R, Sessler DI, Kurz A. The effect of altering skin-surface cooling speeds on vasoconstriction and shivering thresholds. Anesth Analg 2011; 113:540-544. |
22 |
Pretorius T, Lix L, Giesbrecht G. Shivering heat production and body fat protect the core from cooling during body immersion, but not during head submersion: a structural equation model. Comput Biol Med 2011; 41:154-158.
doi: 10.1016/j.compbiomed.2011.01.005 pmid: 21295291 |
23 |
Weant KA, Martin JE, Humphries RL, Cook AM. Pharmacologic options for reducing the shivering response to therapeutic hypothermia. Pharmacotherapy 2010; 30:830-841.
doi: 10.1592/phco.30.8.830 pmid: 20653360 |
24 |
Iwamoto S, Takasu A, Sakamoto T. Therapeutic mild hypothermia: effects on coagulopathy and survival in a rat hemorrhagic shock model. J Trauma 2010; 68:669-675.
doi: 10.1097/TA.0b013e3181a0fbb3 pmid: 19935114 |
25 |
Wu X, Stezoski J, Safar P, Nozari A, Tisherman SA. After spontaneous hypothermia during hemorrhagic shock, continuing mild hypothermia (34 degrees C) improves early but not late survival in rats. J Trauma 2003; 55:308-316.
doi: 10.1097/01.TA.0000079366.23533.1E pmid: 12913642 |
26 |
Mader TJ, Walterscheid JK, Kellogg AR, Lodding CC. The feasibility of inducing mild therapeutic hypothermia after cardiac resuscitation using iced saline infusion via an intraosseous needle. Resuscitation 2010; 81:82-86.
pmid: 19913974 |
27 |
Moore EE. Staged laparotomy for the hypothermia, acidosis, and coagulopathy syndrome. Am J Surg 1996; 172:405-410.
pmid: 8942535 |
28 |
Behringer W, Safar P, Wu X, Nozari A, Abdullah A, Stezoski SW. et al. Veno-venous extracorporeal blood shunt cooling to induce mild hypothermia in dog experiments and review of cooling methods. Resuscitation 2002; 54:89-98.
doi: 10.1016/s0300-9572(02)00046-1 pmid: 12104113 |
29 |
Lee KR, Chung SP, Park IC, Kim SH. Effect of induced and spontaneous hypothermia on survival time of uncontrolled hemorrhagic shock rat model. Yonsei Med J 2002; 43:511-517.
doi: 10.3349/ymj.2002.43.4.511 pmid: 12205740 |
30 |
Wenzel V, Russo SG, Arntz HR, Bahr J, Baubin MA, Böttiger BW. et al. Comments on the 2010 guidelines on cardiopulmonary resuscitation of the European Resuscitation Council. Anaesthesist 2010; 59:1105-1123.
doi: 10.1007/s00101-010-1820-9 pmid: 21125214 |
[1] | Ruo Wu, Luo-gen Peng, Hui-min Zhao. Diverse coagulopathies in a rabbit model with different abdominal injuries [J]. World Journal of Emergency Medicine, 2017, 8(2): 141-147. |
[2] | Yi Han, Zhen-ju Song, Chao-yang Tong, Chun-sheng Li. Effects of hypothermia on the liver in a swine model of cardiopulmonary resuscitation [J]. World Journal of Emergency Medicine, 2013, 4(4): 298-303. |
[3] | Bao-di Sun, Hong-mei Liu, Shi-nan Nie. S100B protein in serum is elevated after global cerebral ischemic injury [J]. World Journal of Emergency Medicine, 2013, 4(3): 165-168. |
[4] | Jian-guo Zhang, Xiao-juan Chen, Fen Liu, Zhen-guo Zeng, Ke-jian Qian. Lung recruitment maneuver effects on respiratory mechanics and extravascular lung water index in patients with acute respiratory distress syndrome [J]. World Journal of Emergency Medicine, 2011, 2(3): 201-205. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||