World Journal of Emergency Medicine ›› 2015, Vol. 6 ›› Issue (4): 277-282.doi: 10.5847/wjem.j.1920-8642.2015.04.005
• Original Articles • Previous Articles Next Articles
Open Access
Andrew Fu Wah Ho1(
), Pin Pin Pek2, Stephanie Fook-Chong3, Ting Hway Wong4, Yih Yng Ng5, Aaron Sung Lung Wong6, Marcus Eng Hock Ong2
Received:2015-03-28
Accepted:2015-09-10
Online:2015-12-15
Published:2015-12-15
Contact:
Andrew Fu Wah Ho
E-mail:sophronesis@gmail.com
Andrew Fu Wah Ho, Pin Pin Pek, Stephanie Fook-Chong, Ting Hway Wong, Yih Yng Ng, Aaron Sung Lung Wong, Marcus Eng Hock Ong. Prehospital system delay in patients with ST-segment elevation myocardial infarction in Singapore[J]. World Journal of Emergency Medicine, 2015, 6(4): 277-282.
Add to citation manager EndNote|Ris|BibTeX
URL: http://wjem.com.cn/EN/10.5847/wjem.j.1920-8642.2015.04.005
Figure 1.
Components of delay in ST-segment elevation myocardial infarction and recommended time intervals by 2012 European Society of Cardiology (ESC) guideline and 2013 American College of Cardiology Foundation/American Heart Association (ACC/AHA). PCI: percutaneous coronary intervention; EMS: emergency medical services; ESC: European Society of Cardiology; ACC/AHA: American College of Cardiology Foundation/American Heart Association
Table 1
Correlates of pre-hospital system delay (first medical contact to door time)
| Variables | All (n=52) | FC2D<35.5 minutes (n=26) | FC2D>35.5 minutes (n=26) | P value |
|---|---|---|---|---|
| Demographics | ||||
| Age, median (range), years | 56.0 (36.0-79.0) | 54.0 (41.0-74.0) | 58.0 (36.0-79.0) | 0.213 |
| Gender (n, %) | 0.714 | |||
| Male | 43 (82.7) | 21 (80.8) | 22 (84.6) | |
| Female | 9 (17.3) | 5 (19.2) | 4 (15.4) | |
| Race (n, %) | 0.629 | |||
| Chinese | 31 (59.6) | 17 (65.4) | 14 (53.8) | |
| Malay | 9 (17.3) | 5 (19.2) | 4 (15.4) | |
| Indian | 9 (17.3) | 6 (23.1) | 3 (11.5) | |
| Others | 3 (5.8) | 1 (3.8) | 2 (7.7) | |
| Presenting circumstances | ||||
| Chest pain/discomfort (n, %) | 45 (86.5) | 23 (88.5) | 22 (84.6) | 0.685 |
| Incident location (n, %) | 0.780 | |||
| Residential | 29 (55.8) | 14 (53.8) | 15 (57.7) | |
| Non-residential | 23 (44.2) | 12 (46.2) | 11 (42.3) | |
| Pain score, mean | 4.27 | 4.44 | 4.12 | 0.834 |
| Glasgow coma scale score, mean | 14.82 | 14.88 | 14.76 | 0.332 |
| Transport conditions (n, %) | ||||
| Weather conditions | 0.720 | |||
| Sunny-fine | 46 (88.5) | 24 (92.3) | 22 (84.6) | |
| Light rain | 2 (3.8) | 1 (3.8) | 1 (3.8) | |
| Heavy rain | 1 (1.9) | 0 (0) | 1 (3.8) | |
| Windy | 2 (3.8) | 1 (3.8) | 1 (3.8) | |
| Traffic conditions | 0.871 | |||
| Light | 4 (8.0) | 2 (8.3) | 2 (7.7) | |
| Moderate | 43 (86.0) | 21 (87.5) | 22 (84.6) | |
| Heavy | 3 (6.0) | 2 (7.7) | 1 (4.2) | |
| Prehospital interventions by paramedic (n, %) | ||||
| GTN (sublingual or transdermal) | 28 (53.8) | 13 (50.0) | 15 (57.7) | 0.578 |
| Aspirin | 7 (13.5) | 3 (11.5) | 4 (15.4) | 0.685 |
| Process of care intervals, median (range), minute | ||||
| Call-to-dispatch time | 2.48 (1.47-16.55) | 2.04 (1.60-5.02) | 2.92 (1.47-16.55) | 0.023 |
| Dispatch-to-arrival-at-patient time | 8.067 (1.30-22.13) | 5.75 (3.58-12.75) | 9.37 (1.30-22.13) | <0.01 |
| Arrival-at-patient-to-leaving patient time | 13.12 (3.12-32.2) | 10.78 (3.12-19.20) | 14.37 (8.07-32.22) | <0.01 |
| Leaving-patient-to-door time | 9.90 (1.62-32.92) | 7.80 (1.62-17.45) | 12.88 (5.25-32.92) | 0.016 |
| Symptom-to-balloon time | 217 (96.0-3038.0) | 222.0 (104.0-3038.0) | 189.0 (96.0-736.0) | 0.104 |
| Door-to-balloon time | 92.0 (62.0-177.0) | 91.0 (62.0-160.0) | 94.0 (65.0-177.0) | 0.331 |
| 1 | Health Facts Singapore 2012. Ministry of Health Singapore. http://www.moh.gov.sg/content/moh_web/home/statistics/Health_Facts_Singapore/Principal_Causes_of_Death.html. Accessed November 27, 2013. |
| 2 | The top 10 causes of death. World Health Organization Fact Sheets. http://www.who.int/mediacentre/factsheets/fs310/en/index3.html. Accessed November 27, 2013. |
| 3 | Reimer KA, Jennings RB. The "wavefront phenomenon" of myocardial ischemic cell death. II. Transmural progression of necrosis within the framework of ischemic bed size (myocardium at risk) and collateral flow. Lab Invest 1979; 40:633-644. |
| 4 | Gersh BJ, Stone GW, White HD, Holmes DR. Pharmacological facilitation of primary percutaneous coronary intervention for acute myocardial infarction: is the slope of the curve the shape of the future? JAMA 2005; 293:979-986. |
| 5 | Shiomi H, Nakagawa Y, Morimoto T, Furukawa Y, Nakano A, Shirai S, et al. Association of onset to balloon and door to balloon time with long term clinical outcome in patients with ST elevation acute myocardial infarction having primary percutaneous coronary intervention: observational study. BMJ 2012; 3257:1-14. |
| 6 |
Anderson JL, Karagounis La, Califf RM. Meta-analysis of five reported studies on the relation of early coronary patency grades with mortality and outcomes after acute myocardial infarction. Am J Cardiol 1996; 78:1-8.
pmid: 8712096 |
| 7 |
De Luca G, Suryapranata H, Ottervanger JP, Antman EM. Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction: every minute of delay counts. Circulation 2004; 109:1223-1225.
pmid: 15007008 |
| 8 |
Terkelsen CJ, Sørensen JT, Maeng M, Jensen LO, Tilsted HH, Trautner S, et al. System delay and mortality among patients with STEMI treated with primary percutaneous coronary intervention. JAMA 2010; 304:763-771.
pmid: 20716739 |
| 9 | Steg PG, James SK, Atar D, Badano LP, Blömstrom-Lundqvist C, Borger MA, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 2012; 33:2569-2619. |
| 10 |
O'Gara PT, Kushner FG, Ascheim DD, Casey DE Jr, Chung MK, de Lemos JA, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2013; 127:e362-425.
pmid: 23247304 |
| 11 | Srimahachota S, Kanjanavanit R, Boonyaratavej S, Boonsom W, Veerakul G, Tresukosol D, et al. Demographic, management practices and in-hospital outcomes of Thai Acute Coronary Syndrome Registry (TACSR): the difference from the Western world. J Med Assoc Thai 2007; 90 Suppl 1: 1-11. |
| 12 | Song L, Yan H, Hu D, Yang J, Sun Y. Pre-hospital care-seeking in patients with acute myocardial infarction and subsequent quality of care in Beijing. Chin Med J (Engl) 2010; 123:664-669. |
| 13 | Ho AFW, Fook-Chong S, Pek PP, Ng YY, Wong ASL, Ong MEH. Prehospital presentation of patients with ST-segment elevation myocardial infarction in Singapore. Int J Cardiol 2013; 168:4273-4276. |
| 14 |
Tan LL, Wong HB, Poh CL, Chan MY, Seow SC, Yeo TC, et al. Utilisation of emergency medical service among Singapore patients presenting with ST-segment elevation myocardial infarction: prevalence and impact on ischaemic time. Intern Med J 2011; 41:809-814.
pmid: 20546061 |
| 15 | Statistics Singapore. Department of Statistics Singapore. http://www.singstat.gov.sg/statistics/latest_data.html#14. Accessed November 27, 2013. |
| 16 |
Shin SD, Ong MEH, Tanaka H, Ma MH, Nishiuchi T, Alsakaf O, et al. Comparison of emergency medical services systems across Pan-Asian countries: a Web-based survey. Prehosp Emerg Care 2012; 16:477-496.
pmid: 22861161 |
| 17 |
Ong MEH, Chan YH, Anantharaman V, Lau ST, Lim SH, Seldrup J. Cardiac arrest and resuscitation epidemiology in Singapore (CARE I study). Prehosp Emerg Care 2003; 7:427-433.
pmid: 14582091 |
| 18 |
Ong MEH, Wong ASL, Seet CM, Teo SG, Lim BL, Ong PJ, et al. Nationwide improvement of door-to-balloon times in patients with acute ST-segment elevation myocardial infarction requiring primary percutaneous coronary intervention with out-of-hospital 12-lead ECG recording and transmission. Ann Emerg Med 2013; 61:339-347.
doi: 10.1016/j.annemergmed.2012.08.020 pmid: 23021348 |
| 19 |
Huber K, De Caterina R, Kristensen SD, Verheugt FW, Montalescot G, Maestro LB, et al. Pre-hospital reperfusion therapy: a strategy to improve therapeutic outcome in patients with ST-elevation myocardial infarction. Eur Heart J 2005; 26:2063-2074.
doi: 10.1093/eurheartj/ehi413 pmid: 16055497 |
| [1] | Carlos del Pozo Vegas, Ancor Sanz-García, Antonio Dueñas-Ruiz, Pedro de Santos Castro, Ana Gil Contreras, María Blanco González, Alberto Correas Galán, Joan B. Soriano, Raúl López-Izquierdo, Francisco Martín-Rodríguez. Prehospital oxygen-therapy and mortality in patients treated by emergency medical services: a prospective, observational multicenter study [J]. World Journal of Emergency Medicine, 2025, 16(4): 357-366. |
| [2] | Jesús Jurado-Palomo, José Luis Martín-Conty, Begoña Polonio-López, Cristina Rivera Picón, Raúl López-Izquierdo, Carlos del Pozo Vegas, Pedro Ángel de Santos Castro, Ancor Sanz-García, Francisco Martín-Rodríguez. Prehospital critical care drug-therapy and 30-day mortality in patients with acute respiratory disease [J]. World Journal of Emergency Medicine, 2025, 16(1): 43-50. |
| [3] | Hock Peng Koh, Jivanraj R. Nagarajah, Hasnita Hassan, Noel Thomas Ross. Bleeding characteristics and mortality outcomes following ST-elevation myocardial infarction thrombolysis: a 5-year analysis in an Asian population [J]. World Journal of Emergency Medicine, 2024, 15(6): 433-440. |
| [4] | Tian Yan, Ziyin Chen, Shengdong Zou, Zefan Wang, Quan Du, Wenhua Yu, Wei Hu, Yongke Zheng, Keyi Wang, Xiaoqiao Dong, Shuangyong Dong. A prospective cohort study on serum A20 as a prognostic biomarker of aneurysmal subarachnoid hemorrhage [J]. World Journal of Emergency Medicine, 2023, 14(5): 360-366. |
| [5] | Johan L. van Nieuwkerk, M. Christien van der Linden, Rolf J. Verheul, Merel van Loon-van Gaalen, Marije Janmaat, Naomi van der Linden. The impact of prehospital blood sampling on the emergency department process of patients with chest pain: a pragmatic non-randomized controlled trial [J]. World Journal of Emergency Medicine, 2023, 14(4): 257-264. |
| [6] | Bao-tao Huang, Yi-heng Cheng, Bo-sen Yang, Yi-ke Zhang, Fang-yang Huang, Yong Peng, Xiao-bo Pu, Mao Chen. The influence of pressure injury risk on the association between left ventricular ejection fraction and all-cause mortality in patients with acute myocardial infarction 80 years or older [J]. World Journal of Emergency Medicine, 2023, 14(2): 112-121. |
| [7] | Li Li, Li-ying Lin, Yuan-qiang Lu. Analysis of imaging characteristics of blunt traumatic aortic dissection: an 8-year experience [J]. World Journal of Emergency Medicine, 2022, 13(5): 361-366. |
| [8] | Guang-mei Wang, Yong Li, Shuo Wu, Wen Zheng, Jing-jing Ma, Feng Xu, Jia-qi Zheng, He Zhang, Jia-li Wang, Yu-guo Chen. The combination of creatine kinase-myocardial band isoenzyme and point-of-care cardiac troponin/ contemporary cardiac troponin for the early diagnosis of acute myocardial infarction [J]. World Journal of Emergency Medicine, 2022, 13(3): 163-168. |
| [9] | Wei-xian Xu, Yuan-yuan Fan, Yao Song, Xin Liu, Hui Liu, Li-jun Guo. Prognostic differences of catestatin among young and elderly patients with acute myocardial infarction [J]. World Journal of Emergency Medicine, 2022, 13(3): 169-174. |
| [10] | Qian-lin Gu, Peng Jiang, Hui-fen Ruan, Hao Tang, Yang-bing Liang, Zhong-fu Ma, Hong Zhan. The expression of oxidative stress genes related to myocardial ischemia reperfusion injury in patients with ST-elevation myocardial infarction [J]. World Journal of Emergency Medicine, 2022, 13(2): 106-113. |
| [11] | Tian Xu, Ya Li, Li-ding Zhao, Guo-sheng Fu, Wen-bin Zhang. Predictors of recurrent angina in patients with no need for secondary revascularization [J]. World Journal of Emergency Medicine, 2021, 12(1): 42-47. |
| [12] | Guo-xiong Chen, Hong-na Wang, Jin-lin Zou, Xiao-xu Yuan. Effects of intracoronary injection of nicorandil and tirofiban on myocardial perfusion and short-term prognosis in elderly patients with acute ST-segment elevation myocardial infarction after emergency PCI [J]. World Journal of Emergency Medicine, 2020, 11(3): 157-163. |
| [13] | Jun Jiang, Nai-liang Tian, Han-bin Cui, Chang-ling Li, Xian-bao Liu, Liang Dong, Yong Sun, Xiao-min Chen, Shao-liang Chen, Bo Xu, Jian-an Wang. Post-dilatation improves stent apposition in patients with ST-segment elevation myocardial infarction receiving primary percutaneous intervention: A multicenter, randomized controlled trial using optical coherence tomography [J]. World Journal of Emergency Medicine, 2020, 11(2): 87-92. |
| [14] | Hong-yi Wu, Ju-ying Qian, Qi-bing Wang, Jun-bo Ge. An unexpected electrocardiogram sign of subacute left ventricular free wall rupture: Its early awareness may be lifesaving [J]. World Journal of Emergency Medicine, 2020, 11(2): 117-119. |
| [15] | Wei He, Yue-yang You, Kai Sun, Chen Xie, Yue Ming, Li-na Yu, Feng-jiang Zhang, Min Yan. Admission delay is associated with worse surgical outcomes for elderly hip fracture patients: A retrospective observational study [J]. World Journal of Emergency Medicine, 2020, 11(1): 27-32. |
| Viewed | ||||||
|
Full text |
|
|||||
|
Abstract |
|
|||||
