Progress in research into the genes associated with venous thromboembolism

doi:10.5847/wjem.j.1920-8642.2015.02.003

Abstract

Abstract:

BACKGROUND: Venous thromboembolism (VTE), including both deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common, lethal disorder that affects hospitalized and non-hospitalized patients. This study aimed to review the progress in the research into VTE.
DATA SOURCES: We reviewed the studies about VTE and verified different genetic polymoriphisms of VTE.
RESULTS: The pathogenesis of VTE involves hereditary and acquired factors. Many studies indicated that the disorder of coagulation and fibirnolytic system is of utmost importance to this disease. Genetic polymoriphism-related VTE demonstrated significant differences among geographies and ethnicities.
CONCLUSION: VTE has many risk factors, but genetic factors play an important role.

Key words: Venous thrombosis, Gene, Hereditary, Polymoriphism

Lian-xing Zhao, Bo Liu, Chun-sheng Li. Progress in research into the genes associated with venous thromboembolism[J]. World Journal of Emergency Medicine, 2015, 6(2): 100-104.

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