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World Journal of Emergency Medicine ›› 2020, Vol. 11 ›› Issue (3): 164-168.doi: 10.5847/wjem.j.1920-8642.2020.03.006

• Original Articles • Previous Articles     Next Articles

Morbidity and mortality risk factors in emergency department patients with Acinetobacter baumannii bacteremia

Rui-xue Sun1, Priscilla Song2, Joseph Walline3, He Wang4, Ying-chun Xu4, Hua-dong Zhu1, Xue-zhong Yu1, Jun Xu1()   

  1. 1 Emergency Department, Peking Union Medical College Hospital, Beijing 100010, China
    2 Department of Anthropology, Washington University in Saint Louis, Saint Louis 63101, USA
    3 Division of Emergency Medicine, Saint Louis University, Saint Louis 63101, USA
    4 Laboratory Department, Peking Union Medical College Hospital, Beijing, China
  • Received:2019-06-06 Accepted:2020-01-26 Online:2020-07-01 Published:2020-07-01
  • Contact: Jun Xu


BACKGROUND: Acinetobacter baumannii (AB) bacteremia is an increasingly common and often fatal nosocomial infection. Identification of morbidity and mortality risk factors for AB bacteremia in emergency department (ED) patients may provide ways to improve the clinical outcomes of these patients.

METHODS: The records for 51 patients with AB bacteremia and 51 patients without AB infection were collected and matched in a retrospective case-control study between 2013 and 2015 in a single-center ED. Risk factors were analyzed by Chi-square and multivariate logistic regression statistical models.

RESULTS: A significant risk factor for morbidity was the presence of a central venous catheter (CVC) (P<0.001). The mortality rate for the 51 patients with AB bacteremia was 68.6%. Risk factors for mortality were the presence of a CVC (P=0.021) and an ED stay longer than two weeks (P=0.015).

CONCLUSION: AB infections lead to high morbidity and mortality. The presence of a CVC was associated with higher morbidity and mortality in patients with AB bacteremia. Avoiding CVC insertions may improve outcomes in ED patients with AB bacteremia.

Key words: Acinetobacter baumannii, Bacteremia, Morbidity, Mortality