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世界急诊医学杂志(英文) ›› 2013, Vol. 4 ›› Issue (2): 151-153.doi: 10.5847/wjem.j.issn.1920-8642.2013.02.012

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  • 收稿日期:2012-12-12 接受日期:2013-03-25 出版日期:2013-06-15 发布日期:2013-06-15

Meningitis secondary to Cryptococcus gattii, an emerging pathogen affecting immunocompetent hosts

Laura Cookman(), Maria Hugi   

  1. Department of Emergency Medicine, Madigan Army Medical Center, Tacoma, WA 98431, USA
  • Received:2012-12-12 Accepted:2013-03-25 Online:2013-06-15 Published:2013-06-15
  • Contact: Laura Cookman E-mail:laura.cookman@amedd.army.mil

Abstract:

BACKGROUND: Meningitis continues to be one of the most important infections diagnosed and treated by emergency physicians. Despite the advent of anti-infective therapy, meningitis carries a mortality rate of 20%-40%. In this study, we describe the first reported emergency medicine case of meningitis associated with Cryptococcus gattii to alert providers of this insidious, emerging global pathogen infecting immunocompetent individuals.
METHODS: We provided a case report and accompanying review of the literature. A MEDLINE search for the term Cryptoccocus gattii was performed to obtain background information on Cryptococcus gattii.
RESULTS: After two months of hospitalization, the patient was eventually discharged neurologically intact except for a continued mild bilateral hearing deficit.
CONCLUSION: Cryptococcus gattii is an emerging world pathogen, which affects otherwise healthy, immunocompetent patients and requires timely identification and treatment in order to prevent severe neurological sequelae.

Key words: Meningitis, Cryptococcus gattii