ICU-acquired weakness in critically ill patients at risk of malnutrition: risk factors, biomarkers, and early enteral nutrition impact

Qingliu Zheng, Changyun Liu, Lingying Le, Qiqi Wu, Zhihong Xu, Jiyan Lin, Qiuyun Chen

Table 2. The multivariable logistic regression analysis of risk factors for ICU-AW

Parameters ICU-AW (n=75) Non-ICU-AW (n =105) OR 95% CI P-value Male, n 45/75 68/105 0.210 0.064-0.994 0.010 Age, years, median (IQR) 74.0 (67.0-84.0) 73.0 (65.5-82.0) 1.132 1.058-1.326 <0.001 EEN, n 32/75 64/105 0.280 0.889-0.887 0.029 MV, n 18/75 13/105 2.212 1.546-4.065 0.032 BMI, kg/m2, median (IQR) 19.6 (17.8-21.6) 21.0 (19.4-20.8) 0.613 0.451-0.831 0.002 IL-6, pg/mL, median (IQR) 63.2 (42.3-78.3) 58.3 (36.1-66.9) 1.005 0.981-1.560 0.687 TRF, g/L, median (IQR) 2.5 (2.3-3.3) 2.6 (2.1-2.9) 0.327 0.126-1.099 0.741 Cr, μmol/L, median (IQR) 124.0 (105.0-198.0) 99.0 (87.0-111.0) 1.347 1.197-1.986 <0.001 BUN, mmol/L, median (IQR) 11.8 (10.5-12.8) 9.1 (7.8-10.2) 2.183 1.518-3.139 <0.001 ALB, g/L, median (IQR) 35.2 (33.2-37.5) 33.8 (32.5-32.7) 1.179 0.930-1.495 0.174