Molecular mechanism of Xuebijing in treating pyogenic liver abscess complicated with sepsis

Wei Zhou, Maiying Fan, Xiang Li, Fang Yu, En Zhou, Xiaotong Han

Table 1. Binding energies of IL-1β, IL-6, and TNF with the active ingredient of Xuebijing

Target protein Active ingredient Binding energy (kcal/mol) IL-1β Quercetin -7.3 IL-6 Quercetin -6.9 IL-6 Luteolin -7.2 IL-6 Paeoniflorin -6.6 TNF Quercetin -9.2 TNF Luteolin -9.2 TNF Kaempferol -9.5 TNF Cryptotanshinone -8.6 TNF Paeoniflorin -10.5