Effects of mesencephalic astrocyte-derived neurotrophic factor on sepsis-associated acute kidney injury

Saifeng Chen, Xuewei Hao, Guo Chen, Guorong Liu, Xiaoyan Yuan, Peiling Shen, Dongfeng Guo

Figure 1. Expression of MANF in the kidney and serum of mice. A: Western blotting analysis of MANF in protein extracts from the kidney tissue of the S-AKI mice at different time; B: Western blotting analysis of MANF levels in protein extracts from the kidney tissue among different groups at 48 h; C: MANF in the serum at different time detected by the MANF ELISA kit. MANF: mesencephalic astrocyte-derived neurotrophic factor; S-AKI: sepsis-associated acute kidney injury; n.s.: no significance. *P<0.05, **P<0.01, ***P<0.001.