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Cardiopulmonary prognosis of prophylactic endotracheal intubation in patients with upper gastrointestinal bleeding undergoing endoscopy
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Yufang Lin, Fei’er Song, Weiyue Zeng, Yichi Han, Xiujuan Chen, Xuanhui Chen, Yu Ouyang, Xueke Zhou, Guoxiang Zou, Ruirui Wang, Huixian Li, Xin Li
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Table 1. Baseline characteristics of the PEI group and the non-PEI group—crude and adjusted
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| Variables | Unmatched data | | Matched data | | PEI (n=108) | Non-PEI (n=838) | P-value | | PEI (n=50) | Non-PEI (n=100) | P-value | | Age, year | 63.00 (52.00-74.00) | 65.00 (53.00-76.00) | 0.087a | | 64.00 (56.75-74.25) | 64.00 (56.75-76.00) | 0.952a | | Male | 63 (58.3) | 494 (58.9) | 0.902a | | 28 (56.0) | 50 (50.0) | 0.488a | | BMI, kg/m2 | 28.30 (23.92-33.49) | 26.83 (23.02-31.60) | 0.168a | | 28.41 (24.46-33.19) | 26.81 (24.43-30.93) | 0.195a | | Heart rate, beat/min | 94.00 (79.25-107.25) | 92.00 (82.00-104.00) | 0.450a | | 95.00 (77.00-111.00) | 92.00 (80.25-104.75) | 0.825a | | Systolic pressure, mmHg | 113.00 (103.00-131.00) | 119.00 (107.00-133.00) | 0.029a | | 114.50 (102.75-129.70) | 119.00 (110.25-125.75) | 0.472a | | Caucasian | 76 (70.4) | 646 (77.1) | 0.353 | | 34 (68.0) | 76 (76.0) | 0.716 | Use of sedative during
endoscopy | 25 (23.1) | 66 (7.9) | <0.001 | | 13 (26.0) | 27 (27.0) | 0.896 | Use of vasopressors
before endoscopy | 32 (29.6) | 78 (9.3) | <0.001 | | 10 (20.0) | 13 (13.0) | 0.262 | Red blood cells infusion
before endoscopy | 68 (63.0) | 442 (52.7) | 0.045 | | 30 (60.0) | 43 (43.0) | 0.050 | | APACHE Ⅳ score | 79.50 (66.25-91.75) | 54.00 (45.00-65.00) | <0.001a | | 68.99±2.58 | 66.63±1.99 | 0.319b | | CCI <4 | 98 (90.7) | 796 (95.0) | 0.068 | | 47 (94.0) | 91 (91.0) | 0.750 | | AIMS65 score | 2.00 (2.00-3.00) | 1.00 (1.00-2.00) | <0.001a | | 2.00 (1.00-2.00) | 1.00 (1.00-2.00) | 0.529a | | Glasgow Coma Scale | 12.00 (9.00-15.00) | 15.00 (15.00-15.00) | <0.001a | | 15.00 (15.00-15.00) | 15.00 (14.25-15.00) | 0.616a | | MELD score | 11.26 (6.37-18.90) | 7.58 (4.35-13.06) | 0.001a | | 10.46 (6.57-14.47) | 11.13 (5.48-17.09) | 0.739a | Ongoing active hematemesis,
agitation, or encephalopathy
before endoscopy | 25 (23.1) | 238 (28.4) | 0.251 | | 11 (22.0) | 36 (36.0) | 0.081 | | INR | 1.30 (1.20-1.67) | 1.30 (1.10-1.40) | 0.001a | | 1.35 (1.19-1.50) | 1.35 (1.10-1.63) | 0.848a | | Total billirubin, mg/dL | 0.80 (0.80-2.47) | 0.80 (0.50-1.20) | <0.001a | | 1.10 (0.67-1.30) | 1.10 (0.50-1.87) | 0.615a | | Creatinine, mg/dL | 0.95 (0.77-1.34) | 0.90 (0.71-1.27) | 0.231a | | 1.03 (0.83-1.33) | 1.03 (0.80-1.94) | 0.851a | | Hemoglobin, g/dL | 8.80 (7.80-9.9) | 8.60 (7.80-9.60) | 0.226a | | 9.14±0.27 | 8.72±0.17 | 0.168b | | History of cirrhosis | 39 (36.1) | 175 (20.9) | <0.001 | | 15 (30.0) | 34 (34.0) | 0.622 | | History of heart disease a | 16 (14.8) | 204 (24.3) | 0.027 | | 9 (18.0) | 21 (21.0) | 0.665 | | History of lung disease b | 17 (15.7) | 159 (19.0) | 0.416 | | 10 (20.0) | 20 (20.0) | 1.000 | | Position of bleeding | | Varices | 26 (24.1) | 119 (14.2) | 0.007 | | 11 (22.0) | 14 (14.0) | 0.215 | | Ulcer | 17 (15.7) | 98 (11.7) | 0.226 | | 6 (12.0) | 13 (13.0) | 0.862 |
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