| Characteristics | Favorable neurological outcome (n=34) | Unfavorable neurological outcome (n=88) | t/χ2/Z | P-value | | Age, years, mean±SD | 52.35±14.76 | 49.28±17.02 | 0.925 | 0.357 | | Male, n (%) | 22 (64.7) | 67 (76.1) | 1.624 | 0.203 | | Comorbidities, n (%) | | | | | | Hypertension | 14 (41.2) | 30 (34.1) | 0.534 | 0.465 | | Diabetes | 8 (23.5) | 17 (19.3) | 0.267 | 0.605 | | Coronary artery disease | 2 (5.9) | 8 (9.1) | 0.045 | 0.833 | | OHCA, n (%) | 7 (20.6) | 39 (44.3) | 5.880 | 0.015 | | Witnessed, n (%) | 34 (100) | 80 (90.9) | 1.991 | 0.158 | | Bystander CPR, n (%) | 34 (100) | 73 (83.0) | 5.122 | 0.024 | | Cardiac etiology, n (%) | 27 (79.4) | 68 (77.3) | 0.065 | 0.799 | | Initial non-shockable rhythm, n (%) | 23 (67.6) | 44 (50.0) | 3.085 | 0.079 | | Resuscitation duration, min, median (IQR) | 40.5 (17.5-55.0) | 50.0 (34.0-82.3) | -2.639 | 0.008 | | ECMO duration, h, median (IQR) | 141.5 (122.8-187.8) | 94.4 (49.3-169.3) | -3.278 | 0.001 | | Length of stay in hospital, d, median (IQR) | 19 (15-27) | 5 (3-11) | -6.609 | <0.001 | | GCS score after ECPR, median (IQR) | 9 (8-12) | 3 (3-4) | -7.765 | <0.001 | | Prognostic predictors | | | | | | GCS-M ≤2, n (%) | 5 (14.7) | 81 (92.0) | 70.522 | <0.001 | | Pupillary/corneal reflex absence, n (%) | 0 (0) | 51 (58.0) | 33.859 | <0.001 | | GWR-basal ganglia, median (IQR) | 1.25 (1.20-1.27) | 1.14 (1.08-1.19) | -5.977 | <0.001 | | NSE, ng/mL, median (IQR) | 44.6 (38.3-60.7) | 188.5 (88.1-370.0) | -6.972 | <0.001 | | Laboratory parameters, median (IQR) | | | | | | Hemoglobin, g/L | 116.5 (101.0-132.3) | 111.0 (84.0-129.0) | -1.385 | 0.166 | | pH | 7.41 (7.31-7.52) | 7.22 (6.96-7.36) | -4.046 | <0.001 | | Lactate, mmol/L | 3.1 (1.1-11.5) | 10.2 (4.0-15.6) | -2.854 | 0.004 | | Glucose, mmol/L | 9.5 (6.7-11.7) | 10.1 (7.1-13.5) | -0.504 | 0.614 | | Albumin, g/L | 33.8 (30.3-39.3) | 31.8 (26.5-39.2) | -1.008 | 0.313 | | ALT, U/L | 159.0 (102.1-309.6) | 306.1 (120.5-801.5) | -2.438 | 0.015 | | Aspartate aminotransferase, U/L | 420.3 (170.1-932.0) | 926.7 (364.6-2176.5) | -2.889 | 0.004 | | Total bilirubin, μmol/L | 14.0 (10.8-19.9) | 20.1 (13.1-32.2) | -2.204 | 0.028 | | Creatinine, μmol/L | 96.1 (69.0-137.7) | 76.5 (103.2-148.2) | -1.074 | 0.283 | | Potassium, mmol/L | 3.9 (3.6-4.3) | 4.5 (3.8-5.2) | -3.489 | <0.001 | | Magnesium, mmol/L | 0.9 (0.8-1.0) | 1.0 (0.9-1.1) | -1.994 | 0.046 | | Phosphate, mmol/L | 1.0 (0.7-1.2) | 1.2 (0.8-2.1) | -2.778 | 0.005 | | Calcium, mmol/L | 2.1 (2.0-2.2) | 1.9 (1.6-2.1) | -3.907 | <0.001 | | Ion shift index | 2.69 (2.51-3.07) | 3.74 (3.15-4.57) | -6.504 | <0.001 |
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