The relationship between physical activity in early pregnancy and hypertensive disorders of pregnancy: a cohort study in Chinese women
Qian Lu, Shi-jiao Yan, Huan-jun Chen, Xiong-fei Pan, Yi-xiang Ye, Xing-yue Song, Ri-xing Wang, Chuan-zhu Lyu
Table 1. Characteristics of the study participants by GH and PE
Characteristics GH P-value a PE P-value b
Case (n=126) Control (n=6,694) Case (n=52) Control (n=6,768)
Age 0.520 0.779
<25 years 38 (30.2) 2,068 (30.9) 15 (28.8) 2,091 (30.9)
25-29 years 54 (42.8) 3,102 (46.3) 23 (44.2) 3,133 (46.3)
≥30 years 34 (27.0) 1,524 (22.8) 14 (26.9) 1,544 (22.8)
Occupations 0.342 0.845
No 57 (45.2) 3,314 (49.5) 25 (48.1) 3,346 (49.4)
Yes 69 (54.8) 3,380 (50.5) 27 (51.9) 3,422 (50.6)
Education level 0.176 0.843
Senior high school or below 66 (52.4) 3,908 (58.4) 31 (59.6) 3,943 (58.3)
Above senior high school 60 (47.6) 2,786 (41.6) 21 (40.4) 2,825 (41.7)
Annual household income 0.827 0.103
Less than 50,000 yuan 55 (43.7) 2,857 (42.7) 28 (53.8) 2,884 (42.6)
≥50,000 yuan 71 (56.3) 3,837 (57.3) 24 (46.2) 3,884 (57.4)
Family history of hypertension 0.001 0.013
No 94 (74.6) 5,723 (85.5) 38 (73.1) 5,779 (85.4)
Yes 32 (25.4) 971 (14.5) 14 (26.9) 989 (14.6)
Pre‐pregnancy BMI <0.001 0.004
<18.5 kg/m2 11 (8.9) 1,174 (17.9) 3 (6.0) 1,182 (17.8)
18.5-24.0 kg/m2 71 (57.7) 4,494 (68.4) 34 (68.0) 4,531 (68.2)
24.0-28.0 kg/m2 28 (22.8) 716 (10.9) 8 (16.0) 736 (11.1)
≥28.0 kg/m2 13 (10.6) 189 (2.9) 5 (10.0) 197 (3.0)
History of HDP <0.001 0.820
No 78 (97.5) 4,417 (99.9) 29 (100.0) 4,466 (99.8)
Yes 2 (2.5) 6 (0.1) 0 (0.0) 8 (0.2)
Parity 0.042 0.144
0 81 (64.3) 3,694 (55.2) 34 (65.4) 3,741 (55.3)
≥1 45 (35.7) 3,000 (44.8) 18 (34.6) 3,027 (44.7)
Diabetes mellitus 0.014 0.817
No 125 (99.2) 6,688 (99.9) 52 (100) 6,761 (99.9)
Yes 1 (0.8) 6 (0.1) 0 (0.0) 7 (0.1)
Tobacco use 0.409 0.560
Current 1 (0.8) 122 (1.8) 0 (0.0) 123 (1.8)
Former 9 (7.1) 339 (5.1) 2 (3.8) 346 (5.1)
Never 116 (92.1) 6,233 (93.1) 50 (96.2) 6,299 (93.1)
Alcohol use 0.175 0.601
Current 0 (0.0) 21 (0.3) 0 (0.0) 21 (0.3)
Former 18 (14.3) 1,379 (20.6) 8 (15.4) 1,389 (20.5)
Never 108 (85.7) 5,294 (79.1) 44 (84.6) 5,358 (79.2)
SBP, mmHg 117.5 (110.0-125.0) 108.0 (102.0-114.0) <0.001 113.5 (109.5-123.9) 108.0 (102.0-114.5) <0.001
DBP, mmHg 78.0 (72.5-83.6) 72.5 (67.0-77.5) <0.001 76.8 (69.8-82.3) 72.5 (67.0-77.5) 0.001