Over-expression of programmed death-ligand 1 and programmed death-1 on antigen-presenting cells as a predictor of organ dysfunction and mortality during early sepsis: a prospective cohort study

Jia-bao Li, Miao-rong Xie, Mei-li Duan, Ya-nan Yu, Chen-chen Hang, Zi-ren Tang, Chun-sheng Li

Figure 1. Surface biomarker expression on leukocyte subsets in controls (n=40) and patients with sepsis (n=121) or septic shock (n=77). PD-1 and PD-L1 expression was evaluated on B cells (A, E), monocytes (B, F), myeloid dendritic cells (mDCs) (C, G), and plasmacytoid dendritic cells (pDCs) (D, H). *P<0.05. ns: no significance. PD-L1: programmed death-ligand 1; PD-1: programmed death-1.