Initial venous lactate levels as a predictor of mortality in severe sepsis: a single-center retrospective cohort study

Thidathit Prachanukool, Pitsucha Sanguanwit, Karn Suttapanit Chaiyaporn Yuksen, Piraya Vichiensanth

Table 2. Performance of initial venous lactate and initial arterial lactate for predicting outcomes

Outcomes	Calibration			Discrimination
Outcomes	HL chi²	P-value	O/E ratio (95% CI)	AUROC curve (95% CI)	P-value
7-d hospital mortality	3.38	0.493	0.96 (0.73-1.19)	0.67 (0.60-0.74)	0.001
Initial venous lactate (n=460)	3.38	0.493	0.96 (0.73-1.19)	0.67 (0.60-0.74)	0.001
Initial arterial lactate (n=433)	2.42	0.654	0.97 (0.74-1.20)	0.69 (0.62-0.76)	0.001
28-d hospital mortality	5.69	0.227	1.00 (0.84-1.16)	0.65 (0.60-0.71)	0.001
Initial venous lactate (n=460)	5.69	0.227	1.00 (0.84-1.16)	0.65 (0.60-0.71)	0.001
Initial arterial lactate (n=433)	2.89	0.583	1.00 (0.84-1.17)	0.66 (0.60-0.72)	0.001
Vasopressor use on day one	5.46	0.492	1.00 (0.89-1.11)	0.62 (0.57-0.68)	0.001
Initial venous lactate (n=460)	5.46	0.492	1.00 (0.89-1.11)	0.62 (0.57-0.68)	0.001
Initial arterial lactate (n=433)	6.46	0.376	1.00 (0.89-1.12)	0.60 (0.55-0.66)	0.001
Ventilator use on day one	11.32	0.021	1.00 (0.92-1.08)	0.54 (0.48-0.60)	0.150
Initial venous lactate (n=460)	11.32	0.021	1.00 (0.92-1.08)	0.54 (0.48-0.60)	0.150
Initial arterial lactate (n=433)	8.00	0.165	1.00 (0.92-1.07)	0.58 (0.53-0.64)	0.010