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Fei Shao, Xian Shi, Shu-hua Huo, Qing-yu Liu, Ji-xue Shi, Jian Kang, Ping Gong, Sheng-tao Yan, Guo-xing Wang, Li-jie Qin, Fei Wang, Ke Feng, Feng-ying Chen, Yong-jie Yin, Tao Ma, Yan Li, Yang Wu, Hao Cui, Chang-xiao Yu, Song Yang, Wei Gan, Sai Wang, Liu-ye-zi Du, Ming-chen Zhao, Zi-ren Tang, Shen Zhao
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| Characteristics | Overall (n=175) | Survivor (n=143) | Non-survivor (n=32) | P-value | | Demographic data | | Sex, n (%) | | | | | | Female | 61 (34.86) | 49 (34.27) | 12 (37.50) | 0.887 | | Male | 114 (65.14) | 94 (65.73) | 20 (62.50) | | | Age, years, median (interquartile range) | 64 (51-75) | 64 (50-75) | 63 (53-71) | 0.960 | | Condition of hospitalization | | Initial mean arterial pressure, n (%) | | | | | 70-105 mmHg | 117 (66.86) | 103 (72.03) | 14 (43.75) | <0.001 | | <70 mmHg | 29 (16.57) | 14 (9.79) | 15 (46.88) | | | >105 mmHg | 29 (16.57) | 26 (18.18) | 3 (9.38) | | | Invasive ventilation, n (%) | | | | | | No | 111 (63.43) | 107 (74.83) | 4 (12.50) | <0.001 | | Yes | 64 (36.57) | 36 (25.17) | 28 (87.50) | | | Core temperature, °C, median (interquartile range) | 40.0 (38.1-41.0) | 39.7 (37.5-41.0) | 40.8 (40.0-42.0) | 0.002 | | Maximum heart rate, n (%) | | | | | | 60-100 beats/min | 52 (29.71) | 49 (34.27) | 3 (9.38) | 0.010 | | >100 beats/min | 123 (70.29) | 94 (65.73) | 29 (90.62) | | | Glasgow admission prediction score, median (interquartile range) | 8 (5-12) | 8 (6-14) | 5 (3-7) | <0.001 | | Hemofiltration, n (%) | | | | | | No | 147 (84.00) | 129 (90.21) | 18 (56.25) | <0.001 | | Yes | 28 (16.00) | 14 (9.79) | 14 (43.75) | | | Intravascular hypothermia, n (%) | | | | | No | 164 (93.71) | 133 (93.01) | 31 (96.88) | 0.692 | | Yes | 11 (6.29) | 10 (6.99) | 1 (3.12) | | | Mild hypothermia in vitro, n (%) | | | | | No | 106 (60.57) | 90 (62.94) | 16 (50.00) | 0.249 | | Yes | 69 (39.43) | 53 (37.06) | 16 (50.00) | | | Laboratory tests on day 1 | | | | | | White blood cell count (WBC), n (%) | | | | | | (3.5-9.5)×109/L | 60 (34.29) | 53 (37.06) | 7 (21.88) | 0.153 | | >9.5×109/L | 115 (65.71) | 90 (62.94) | 25 (78.12) | | | Red blood cell count (RBC), n (%) | | | | | | (3.8-5.1)×109/L | 129 (73.71) | 103 (72.03) | 26 (81.25) | 0.704 | | <3.8×109/L | 38 (21.71) | 33 (23.08) | 5 (15.62) | | | >5.1×109/L | 8 (4.57) | 7 (4.90) | 1 (3.12) | | | Hemoglobin count (HBG), n (%) | | | | | | 115-150 g/L | 122 (69.71) | 100 (69.93) | 22 (68.75) | 0.211 | | <115 g/L | 34 (19.43) | 30 (20.98) | 4 (12.50) | | | >150 g/L | 19 (10.86) | 13 (9.09) | 6 (18.75) | | | Platelet count (PLT), n (%) | | | | | | (125-350)×109/L | 92 (52.57) | 80 (55.94) | 12 (37.50) | 0.086 | | <125×109/L | 81 (46.29) | 61 (42.66) | 20 (62.50) | | | >350×109/L | 2 (1.14) | 2 (1.40) | 0 | | | Alanine aminotransferase (ALT), n (%) | | | | | | 7-40 U/L | 72 (41.14) | 67 (46.85) | 5 (15.62) | 0.002 | | >40 U/L | 103 (58.86) | 76 (53.15) | 27 (84.38) | | | Creatine (CRE), n (%) | | | | | | 41.0-81.0 U/L | 59 (33.71) | 56 (39.16) | 3 (9.38) | 0.003 | | >81.0 U/L | 116 (66.29) | 87 (60.84) | 29 (90.62) | | | Potassium, n (%) | | | | | | 3.5-5.3 m/L | 92 (52.57) | 71 (49.65) | 21 (65.62) | 0.053 | | <3.5 m/L | 78 (44.57) | 69 (48.25) | 9 (28.12) | | | >5.3 m/L | 5 (2.86) | 3 (2.10) | 2 (6.25) | | | Calcium, n (%) | | | | | | 2.11-2.52 m/L | 57 (32.57) | 46 (32.17) | 11 (34.38) | 0.440 | | <2.11 m/L | 116 (66.29) | 96 (67.13) | 20 (62.50) | | | >2.52 m/L | 2 (1.14) | 1 (0.70) | 1 (3.12) | | | Myoglobin (MYO), n (%) | | | | | | 0-107 μg/L | 16 (9.14) | 15 (10.49) | 1 (3.12) | 0.311 | | >107 μg/L | 159 (90.86) | 128 (89.51) | 31 (96.88) | | | Brain natriuretic peptide (BNP), n (%) | | | | | | 0-100 pg/mL | 39 (22.29) | 33 (23.08) | 6 (18.75) | 0.767 | | >100 pg/mL | 136 (77.71) | 110 (76.92) | 26 (81.25) | | | Laboratory tests on day 3 | | | | | | WBC, n (%) | | | | | | (3.5-9.5)×109/L | 50 (28.57) | 47 (32.87) | 3 (9.38) | 0.007 | | <3.5×109/L | 2 (1.14) | 1 (0.70) | 1 (3.12) | | | >9.5×109/L | 123 (70.29) | 95 (66.43) | 28 (87.50) | | | HBG, n (%) | | | | | | (115-150)×109/L | 136 (77.71) | 112 (78.32) | 24 (75.00) | 0.567 | | <115×109/L | 36 (20.57) | 29 (20.28) | 7 (21.88) | | | >150×109/L | 3 (1.71) | 2 (1.40) | 1 (3.12) | | | PLT, n (%) | | | | | | (125-350)×109/L | 33 (18.86) | 31 (21.68) | 2 (6.25) | 0.077 | | <125×109/L | 142 (81.14) | 112 (78.32) | 30 (93.75) | | | ALT, n (%) | | | | | | 7-40 U/L | 21 (12.00) | 21 (14.69) | 0 | 0.015 | | >40 U/L | 154 (88.00) | 122 (85.31) | 32 (100.00) | | | AST, n (%) | | | | | | 13-35 U/L | 20 (11.43) | 19 (13.29) | 1 (3.12) | 0.295 | | <13 U/L | 1 (0.57) | 1 (0.70) | 0 | | | >35 U/L | 154 (88.00) | 123 (86.01) | 31 (96.88) | | | International normalized ratio (INR), n (%) | | | | | | 0.8-1.2 | 115 (65.71) | 93 (65.03) | 22 (68.75) | 0.846 | | >1.2 | 60 (34.29) | 50 (34.97) | 10 (31.25) | | | CRE, n (%) | | | | | | 41.0-81.0 U/L | 117 (66.86) | 95 (66.43) | 22 (68.75) | 1 | | <41.0 U/L | 4 (2.29) | 4 (2.80) | 0 | | | >81.0 U/L | 54 (30.86) | 44 (30.77) | 10 (31.25) | | | Potassium, n (%) | | | | | | 3.5-5.3 m/L | 146 (83.43) | 119 (83.22) | 27 (84.38) | 0.392 | | <3.5 m/L | 27 (15.43) | 23 (16.08) | 4 (12.50) | | | >5.3 m/L | 2 (1.14) | 1 (0.70) | 1 (3.12) | | | MYO, n (%) | | | | | | 0-107 μg/L | 19 (10.86) | 19 (13.29) | 0 | | | >107 μg/L | 156 (89.14) | 124 (86.71) | 32 (100.00) | 0.026 | | BNP, n (%) | | | | | | 0-100 pg/mL | 4 (2.29) | 4 (2.80) | 0 | 1 | | >100 pg/mL | 171 (97.71) | 139 (97.20) | 32 (100.00) | |
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