Optimal indicator for changing the filter during the continuous renal replacement therapy in intensive care unit patients with acute kidney injury: A crossover randomized trial

Cheng Hang, Li-jun Liu, Zhao-yun Huang, Jian-liang Zhu, Bao-chun Zhou, Xiao-zhen Li

Table 1. Clinical data of AKI patients before treatment

Parameters Group A (n=27) Group B (n=23) χ2/Z/t P Gender Male 18 (66.7) 16 (69.6) χ2=0.118 0.732 Female 9 (33.3) 7 (30.4) χ2=0.250 0.617 Age, years 62 (38-79) 61 (44-66) Z= -0.681 0.496 Height, cm 167±8 169±9 t= -0.870 0.388 Body weight, kg 70 (60-75) 70 (57-75) Z= -0.283 0.777 APACHE II score 19 (13-23) 17 (13-20) Z= -0.946 0.344 SOFA score 13 (9-16) 11 (8-17) Z= -0.078 0.938 Primary diagnosis Septic shock 17 (63.0) 9 (39.1) χ2=2.462 0.117 Organ failure 1 (3.7) 5 (21.7) χ2=2.667 0.102 Poisoning of drugs or toxins 6 (22.2) 2 (8.7) χ2=2.000 0.157 Cardiac arrest 2 (7.4) 3 (13.0) χ2=0.200 0.655 AKI with unknown causes 1 (3.7) 4 (17.4) χ2=1.800 0.180 Urea nitrogen before treatment, mmol/L 28.9±17.2 26.3±16.8 t=0.553 0.583 Creatinine before treatment, μmol/L 615±650 437±223 t=1.249 0.218 β2-microglobulin before treatment, μg/L 7,746.0±3,891.4 7,309.1±4,696.8 t=0.360 0.721 Cystatin C before treatment, mg/L 1.77±0.72 1.86±0.73 t= -0.414 0.681 Duration of mechanical ventilation, h 141±155 214±277 t= -1.130 0.267 ICU stay, h 229±175 350±370 t= -1.436 0.161 Renal function recovery rate 9 (33.3) 10 (43.5) χ2=0.053 0.819 In-hospital mortality rate 18 (66.7) 13 (56.5) χ2=0.806 0.369