Trichostatin A improves the inflammatory response and liver injury in septic mice through the FoxO3a/autophagy signaling pathway

Mei-jia Shen, Li-chao Sun, Xiao-yu Liu, Meng-chen Xiong, Shan Li, A-ling Tang, Guo-qiang Zhang

Table 2. Comparison of ALT, AST, LC3 II, P62, and FoxO3a in AML12 cells

Parameters Control group TSA group LPS group LPS+TSA group ALT a, U/L 5.05±0.55 14.20±2.20 29.42±0.62** 23.47±0.64## AST a, U/L 9.55±0.65 18.90±3.10 63.52±4.50** 38.51±1.50## LC3 II b 1 1.77±0.02** 1.39±0.01** 1.87±0.01## P62 b 1 0.50±0.01** 0.73±0.01** 0.38±0.01## Foxo3a b 1 2.23±0.02** 1.79±0.01** 3.10±0.07##