Artificial intelligence computed tomography helps evaluate the severity of COVID-19 patients: A retrospective study

Yi Han, Su-cheng Mu, Hai-dong Zhang, Wei Wei, Xing-yue Wu, Chao-yuan Jin, Guo-rong Gu, Bao-jun Xie, Chao-yang Tong

Table 2 Laboratory indices of COVID-19 patients

Parameters All patients (n=117) Non-severe patients (n=77) Severe patients (n=40) P value White blood cell (×109/L) 5.81 (4.23-8.02) 5.52 (4.22-7.38) 7.14 (4.40-10.70) 0.150 Neutrophil (×109/L) 3.88 (2.69-6.34) 3.41 (2.27-4.85) 5.98 (3.63-9.63) <0.001 Lymphocyte (×109/L) 1.04 (0.68-1.50) 1.28 (0.93-1.69) 0.68 (0.52-0.92) <0.001 Monocyte (×109/L) 0.48±0.21 0.52±0.20 0.41±0.21 0.004 CD3+ (/μL) 565 (341-858) 769 (527-1065) 365 (304-540) <0.001 CD4+ (/μL) 348 (228-544) 466 (314-649) 236 (170-314) <0.001 CD8+ (/μL) 192 (118-318) 238 (170-367) 140 (74-186) <0.001 CD19 (/μL) 128 (77-203) 163 (74-211) 111 (77-174) 0.223 CD16+56 (/μL) 112.5 (65.8-185.8) 130 (78-203) 100 (62-162) 0.085 CRP (mg/L) 27.8 (5.0-77.5) 8.1 (5.0-50.9) 103.8 (30.2-175.3) <0.001 PaO2/FiO2 (mmHg) 240.39±147.17 330.69±162.12 215.68±143.27 0.016 IL-2 (pg/mL) 3.62 (3.17-4.08) 3.62 (3.17-4.12) 3.54 (3.13-4.06) 0.646 IL-4 (pg/mL) 3.21 (2.90-3.79) 3.21 (2.84-3.91) 3.22 (2.98-3.63) 0.895 IL-6 (pg/mL) 8.24 (5.59-22.79) 7.90 (4.57-10.92) 16.11 (7.59-102.31) 0.002 IL-10 (pg/mL) 5.91 (4.69-7.95) 5.34 (4.44-6.42) 7.86 (5.46-13.53) 0.005 TNF-α (pg/mL) 3.21 (2.68-5.01) 3.46 (2.66-5.08) 3.18 (2.71-4.01) 0.491 IFN-γ (pg/mL) 3.63 (2.80-5.40) 3.85 (2.71-6.02) 3.47 (2.96-4.33) 0.569 PCT (ng/mL) 0.10 (0.04-0.21) 0.04 (0.03-0.12) 0.19 (0.12-0.40) <0.001