Protective effect of mesenchymal stem cell-derived exosomal treatment of hippocampal neurons against oxygen-glucose deprivation/reperfusion-induced injury

Xiao-fang Guo, Shuang-shuang Gu, Jun Wang, Hao Sun, Yu-juan Zhang, Peng-fei Yu, Jin-song Zhang, Lei Jiang

Figure 1. Identification of MSCs and MSC-Exo. A: the morphology of the MSCs; B: differentiation of MSCs into osteoblasts; C: differentiation of MSCs into adipocytes; D: electron microscopic image of exosomes; E: Western blotting luminograms showing exosomal expressions of CD63 and Alix; F: PKH26-tagged (red fluorescence) exosomes in the neurunal cytoplasm. MSCs: mesenchymal stem cells; MSC-Exo: MSC-derived exosomes.