Anemia and risk of periprocedural cerebral injury detected by diffusion-weighted magnetic resonance imaging in patients undergoing transcatheter aortic valve replacement

Stella Ng, Qi-feng Zhu, Ju-bo Jiang, Chun-hui Liu, Jia-qi Fan, Ye-ming Xu, Xian-bao Liu, Jian-an Wang

Table 4 Linear regression analysis for the prediction of the volume/lesion in ACA/MCA and MCA region (on post-TAVR DW-MRI)

Variables ACA/MCA region MCA region Univariate Multivariate Univariate Multivariate R P-value β t P-value 95% CI R P-value β t P-value 95% CI Age 0.007 0.930 0.025 0.757 Male 0.019 0.813 0.045 0.575 NYHA class 0.195 0.014 -14.361 -2.716 0.007 -24.807 to -3.915 0.106 0.186 STS score 0.027 0.736 0.034 0.674 Medication on admission 0.041 0.610 0.068 0.394 Past history Smoker 0.111 0.166 0.092 0.252 Diabetes mellitus 0.016 0.844 0.069 0.388 Hypertension 0.004 0.960 0.037 0.642 Dyslipidemia 0.121 0.130 0.061 0.443 Prior myocardial infarction 0.059 0.465 0.027 0.740 Prior PCI 0.036 0.649 0.102 0.203 Prior stroke 0.046 0.566 0.027 0.735 Peripheral vascular disease 0.008 0.923 0.066 0.408 Atrial fibrillation 0.119 0.135 0.059 0.458 Anemia 0.152 0.056 16.796 2.243 0.026 2.001 to 31.591 0.163 0.041 0.020 2.039 0.041 0.001 to 0.040 Laboratory data Hemoglobin 0.095 0.237 0.059 0.460 INR 0.103 0.196 0.069 0.390 APTT 0.108 0.175 0.109 0.174 Pre-TAVR echocardiography Mean gradient 0.152 0.056 0.218 2.043 0.043 0.007 to 0.430 0.009 0.910 Aortic valve area 0.038 0.640 0.059 0.458 Maximum velocity 0.179 0.025 0.052 0.519 Carotid stenosis (II+) 0.093 0.243 0.025 0.751 Procedural data Valve types 0.097 0.224 0.197 0.013 -0.025 -2.316 0.022 -0.046 to -0.004 Pre-dilatation 0.011 0.887 0.036 0.651 Post-dilatation 0.075 0.348 0.074 0.355 Procedural time 0.137 0.086 0.139 0.082