Tranexamic acid for major trauma patients in Ireland
Kieran Walsh, Francis O’Keeffe, Louise Brent, Biswadev Mitra
Table 1 Demographics and baseline variables
Variables TXA not administered (n=101) TXA administered (n=133) P-value
Age, n (%)
0-10 years
11-20 years
21-40 years
41-65 years
>65 years

10 (9.90)
6 (5.94)
27 (26.73)
22 (21.78)
36 (35.64)

1 (0.75)
9 (6.77)
50 (37.39)
40 (30.08)
33 (24.81)
0.002
Sex (male), n (%) 55 (54.46) 99 (74.44) 0.001
Injury mechanism, n (%)
Vehicle
Penetrating
High fall
Low fall
Other blunt
Other

19 (18.81)
14 (13.86)
12 (11.88)
44 (43.56)
9 (8.91)
3 (2.97)

68 (51.13)
26 (19.55)
15 (11.28)
17 (12.78)
6 (4.51)
1 (0.75)
<0.001
Penetrating trauma, n (%) 15 (14.85) 30 (22.56) 0.140
Ambulance/helicopter, n (%) 81 (80.20) 128 (96.24) <0.001
ED SBPa, mmHg 77.9±20.5 75.5±21.1 0.390
ED SI >1, n (%) 58 (57.43) 94 (70.68) 0.030
ED GCSb, n (%)
3-8
9-12
13-15

24 (23.76)
7 (6.93)
67 (66.36)

38 (28.57)
12 (9.02)
82 (61.65)
0.610
ED pulse ratea, beats/minute 88.7±32.8 96.4±35.7 0.100
ISS, n (%)
0-12
13-25
>25

31 (30.69)
46 (45.54)
24 (23.76)

29 (21.80)
38 (28.57)
66 (49.62)
<0.001