Left-sided vagus nerve stimulation improves cardiopulmonary resuscitation outcomes in rats as effectively as right-sided vagus nerve stimulation
Wei-jing Shao, Ting-ting Shu, Shuang Xu, Li-cai Liang, Jehane Michael Le Grange, Yu-ran Zhou, He Huang, Yu Cai, Qing Zhang, Peng Sun
Figure 1. Effects of LVNS and RVNS on hemodynamic data. A: HR changes in each group during the VNS period (compared with sham, **P<0.01); B: MAP changes in each group during the VNS period (compared with baseline, **P<0.01); C: number of electric shocks in each group during resuscitation (*P<0.05); D: duration of CPR in each group (*P<0.05); E: survival rate curves in a 72-hour observation period of the sham, CPR, LVNS, and RVNS groups (compared with CPR, *P<0.05); ns: not significant; HR: heart rate; MAP: mean arterial pressure; VNS: vagus nerve stimulation; CPR: cardiopulmonary resuscitation; LVNS: left-sided vagus nerve stimulation; RVNS: right-sided vagus nerve stimulation.