Development of septic shock and prognostic assessment in critically ill patients with coronavirus disease outside Wuhan, China

Ren-qi Yao, Chao Ren, Di Ren, Jin-xiu Li, Ying Li, Xue-yan Liu, Lei Huang, Yong Liu, Mian Peng, Yong-wen Feng, Yong-ming Yao

Table 1 Comparison between septic shock and non-septic shock COVID-19 patients admitted to ICU

Characteristics Septic shock (n=9) Non-septic shock (n=26) P-value Demographic characteristics Age, years, median (IQR) 65.0 (60.0-69.0) 63.0 (59.0-66.3) 0.446 Female, n (%) 3 (33.3) 7 (26.9) 0.694 Complications, n (%) ARDS 9 (100.0) 25 (96.2) 0.437 Secondary infection 9 (100.0) 7 (26.9) <0.001 Acute kidney injury 5 (55.6) 2 (7.7) 0.003 Acute cardiac injury 3 (33.3) 0 (0) 0.003 Acute liver injury 3 (33.3) 0 (0) 0.003 Coagulopathy 3 (33.3) 0 (0) 0.003 Treatments IMV, n (%) 9 (100.0) 9 (34.6) <0.001 MV duration, days, median (IQR) 25.1 (18.6-29.3) 7.4 (4.8-11.4) <0.001 ECMO, n (%) 4 (44.4) 0 (0) <0.001 Vasoactive agents, n (%) 9 (100.0) 1 (3.8) <0.001 Prognosis Onset of symptoms to hospital admission, days, median (IQR) 6.0 (2.0-10.5) 4.0 (2.8-7.0) 0.469 Hospital admission to ICU admission, days, median (IQR) 9.0 (3.0-10.5) 6.5 (3.0-9.3) 0.590 Onset of ICU admission to septic shock, days, median (IQR) 5.0 (3.0-7.0) NA NA Length of stay in hospital, median, days, median (IQR) 33.0 (28.5-34.5) 29.5 (23.0-32.3) 0.086 Length of stay in ICU, days, median (IQR) 24.0 (23.0-26.0) 10.0 (6.0-17.5) <0.001 Discharge from hospital, n (%) 0 (0) 4 (15.4) 0.110 Discharge from ICU, n (%) 4 (44.4) 26 (100.0) <0.001 Death, n (%) 3 (33.3) 0 (0) 0.003