Saddle pulmonary embolism is not a sign of high-risk deterioration in non-high-risk patients: A propensity score-matched study

Dong Jia, Chao Ji, Min Zhao

Table 2 Prognostic factors associated with deterioration

Variables Univariate Multivariate HR (95% CI) P-value HR (95% CI) P-value MPA embolism to non-MPA embolism, n=306 (153:153) MPA embolism 2.13 (1.10-4.12) 0.025* 1.96 (1.01-3.83) 0.047* Saddle MPA embolism 1.75 (0.83-3.68) 0.140 - - Bova score II 1.64 (0.75-3.58) 0.220 0.57 (0.22-1.44) 0.230 Bova score III 5.17 (2.51-10.65) <0.001* 1.51 (0.61-3.74) 0.370 Risk stratification (intermediate-low risk) 1.35 (0.43-4.17) 0.610 1.45 (0.46-4.54) 0.520 Risk stratification (intermediate-high risk) 5.28 (2.19-12.76) <0.001* 5.85 (1.98-17.30) 0.001* Non-saddle MPA embolism to non-MPA embolism,n=220 (110:110) MPA embolism 2.33 (1.06-5.12) 0.034* 2.34 (1.07-5.15) 0.034* Saddle MPA embolism - - - - Bova score II 2.22 (0.84-5.83) 0.011* 0.97 (0.31-3.03) 0.950 Bova score III 6.93 (2.99-16.06) <0.001* 2.80 (0.92-8.54) 0.070 Risk stratification (intermediate-low risk) 3.99 (0.99-15.95) 0.050 3.72 (0.91-14.25) 0.068 Risk stratification (intermediate-high risk) 9.30 (2.76-31.30) <0.001* 5.99 (1.36-26.45) 0.018* Saddle MPA embolism to non-saddle MPA embolism,n=147 (49:98) MPA embolism - - - - Saddle MPA embolism 1.13 (0.57-2.23) 0.720 - - Bova score II 1.28 (0.50-3.31) 0.610 0.67 (0.21-2.09) 0.490 Bova score III 4.00 (1.88-8.49) <0.001* 1.85 (0.63-5.43) 0.260 Risk stratification (intermediate-low risk) 2.01 (0.52-7.76) 0.310 2.12 (0.54-8.42) 0.280 Risk stratification (intermediate-high risk) 4.92 (1.49-16.25) 0.009* 3.94 (0.87-17.73) 0.074 Saddle MPA embolism to non-MPA embolism, n=153 (51:102) MPA embolism - - - - Saddle MPA embolism 1.90 (0.93-3.87) 0.080 1.92 (0.93-3.99) 0.079 Bova score II 1.79 (0.71-4.51) 0.220 0.60 (0.21-1.72) 0.340 Bova score III 6.72 (2.82-16.00) <0.001* 1.99 (0.71-5.53) 0.190 Risk stratification (intermediate-low risk) 1.26 (0.21-7.57) 0.800 1.21 (0.20-7.38) 0.830 Risk stratification (intermediate-high risk) 6.97 (1.65-29.42) 0.008* 7.06 (1.38-36.09) 0.019*