Role of urine studies in asymptomatic febrile neutropenic patients presenting to the emergency department

Hady Zgheib, Aline El Zakhem, Cynthia Wakil, Mohamad Ali Cheaito, Rola Cheaito, Antoine Finianos, Ralphe Bou Chebl, Rima Kaddoura, Nader Al Souky, Imad El Majzoub

Table 3 Diagnostic performance of urinalysis findings at a urine culture cut-off ≥105 cfu/mL, % (95% CI)

Variables Sensitivity Specificity PPV NPV WBC (pyuria) 45.5 (16.8, 76.2) 87.2 (82.6, 90.9) 12.5 (6.5, 22.7) 97.5 (95.9, 98.6) Leukocyte esterase 36.4 (10.9, 69.2) 93.0 (89.3, 95.8) 17.4 (7.9, 34.0) 97.3 (95.9, 98.3) Nitrite 18.2 (2.3, 51.8) 99.6 (98.0, 100.0) 66.7 (16.4, 95.3) 96.8 (95.8, 97.6) Bacteria (bacteriuria) 63.6 (30.8, 89.1) 84.3 (79.4, 88.4) 14.0 (8.8, 21.6) 98.3 (96.3, 99.2) Urine analysis 72.7 (39.0, 94.0) 75.1 (69.5, 80.1) 10.5 (7.2, 15.1) 98.6 (96.3, 99.5)