Role of urine studies in asymptomatic febrile neutropenic patients presenting to the emergency department

Hady Zgheib, Aline El Zakhem, Cynthia Wakil, Mohamad Ali Cheaito, Rola Cheaito, Antoine Finianos, Ralphe Bou Chebl, Rima Kaddoura, Nader Al Souky, Imad El Majzoub

Table 1 Baseline characteristics of patients with positive and negative urine cultures at cut-offs ≥105 cfu/mL and ≥104 cfu/mL

Variables All (n=284) Cut-off ≥105 cfu/mL Cut-off ≥104 cfu/mL Positive UCs (n=11) Negative UCs (n=273) P-value Positive UCs (n=28) Negative UCs (n=256) P-value Age (years), mean±SD 48.5±18.5 63.2±19.5 47.9±18.5 0.007 57.5±19.5 47.5±18.2 0.007 Female, n (%) 139 (48.9) 9 (81.8) 130 (47.6) 0.032 20 (71.4) 119 (46.5) 0.012 Tumor type, n (%) Solid Liquid BMT 133 (47.0) 140 (49.5) 10 (3.5) 6 (54.6) 5 (45.5) 0 (0) 127 (46.7) 135 (49.6) 10 (3.7) 0.843 16 (57.1) 12 (42.9) 0 (0) 117 (45.9) 128 (50.2) 10 (3.9) 0.358 ANC (cells/mm3), median (IQR) 0 (0, 206.5) 0 (0, 189) 0 (0, 208) 0.604 0 (0, 241) 0 (0, 202.5) 0.933 Neutropenia, n (%) Moderate Severe Profound 23 (8.1) 66 (23.2) 195 (68.7) 1 (9.1) 2 (18.2) 8 (72.7) 22 (8.1) 64 (23.4) 187 (68.5) 1.000 1 (3.6) 8 (28.6) 19 (67.9) 22 (8.6) 58 (22.7) 176 (68.8) 0.557 CCI, mean±SD 3.7±2.1 3.7±1.9 3.7±2.2 0.931 4.3±2.2 3.6±2.1 0.110 LOS (days), median (IQR) 4 (3, 7) 3 (2, 8) 4 (3, 7) 0.399 4 (3, 7) 4 (3, 7) 0.914