| Variables | Total (n=2,567) | Survivors (n=1,946) | Non-survivors (n=621) | P | | Age (years) | 63.35 (51.39-75.98) | 62.14 (50.38-74.55) | 68.02 (55.20-79.44) | <0.001 | | Male, n (%) | 1,479 (57.62) | 1,127 (57.91) | 352 (56.68) | 0.589 | | Weight (kg) | 81.1 (68.0-97.1) | 82.3 (70.0-98.2) | 77.9 (64.1-92.3) | <0.001 | | BMI (kg/m2) | 27.91 (24.13-32.91) | 28.23 (24.41-33.09) | 27.08 (22.79-31.98) | <0.001 | | Heart rate (beats per minute) | 88.37 (78.89-98.47) | 88.05(78.96-97.69) | 89.68 (78.90-100.89) | 0.028 | | MAP (mmHg) | 77.25 (71.92-84.17) | 77.79 (72.30-84.17) | 75.85 (70.74-84.51) | 0.073 | | PaO2/FiO2 ratio | 237.83 (193.89-289.95) | 239.17 (194.67-291.77) | 232.50 (191.42-279.47) | <0.001 | | Comorbidities, n (%) | | | | | | Diabetes | 728 (28.36) | 562 (28.88) | 166 (26.73) | 0.301 | | Sepsis | 1,584 (61.71) | 1,165 (59.87) | 419 (67.47) | 0.001 | | Severity of illness | | | | | | SAPS II | 44 (35-55) | 42 (33-52) | 53(44-64) | <0.001 | | ARDS severity, n (%) | | | | | | Mild | 379 (14.76) | 305 (15.67) | 74 (11.92) | <0.001 | | Moderate | 1,023 (39.85) | 816 (41.93) | 207 (33.33) | | Severe | 1,165 (45.38) | 825 (42.39) | 340 (54.75) | | Laboratory data | | | | | | WBC (×109/L) | 12.8 (8.8-18.1) | 12.5 (8.8-17.5) | 14.0 (8.9-19.4) | 0.003 | | RBC (×109/L) | 3.58 (3.10-4.10) | 3.59 (3.11-4.11) | 3.54 (3.06-4.07) | 0.133 | | PLT (×109/L) | 201 (139-276) | 202 (144-270) | 197 (118-294) | 0.056 | | Lactate (mmol/L) | 2.1 (1.4-2.7) | 2.0 (1.3-2.5) | 2.5 (1.7-3.8) | <0.001 | | EOS counts initial (×109/L) | 0.2 (0-1.0) | 0.3 (0-1.0) | 0.1 (0-0.6) | <0.001 | | EOS counts minimum (×109/L) | 0.2 (0-0.9) | 0.2 (0-1.0) | 0.1 (0-0.4) | <0.001 | | EOS counts maximum (×109/L) | 0.4 (0-1.2) | 0.5 (0.1-1.3) | 0.2 (0-1.0) | <0.001 | | pH | 7.35 (7.28-7.42) | 7.36 (7.29-7.42) | 7.33 (7.26-7.41) | <0.001 | | Mechanical ventilation | | | | | | Tidal volume (mL/kg PBW) | 6.65 (5.41-8.04) | 6.56 (5.35-7.95) | 6.85 (5.63-8.21) | 0.001 | | Minute ventilation (L/min) | 9.8 (8.0-12.4) | 9.6 (7.9-12.0) | 10.4 (8.3-13.8) | <0.001 | | Low tidal volume, n (%) | 1,167 (45.46) | 910 (46.76) | 257 (41.38) | 0.019 | | Drug usage, n (%) | | | | | | Corticosteroid use | 436 (16.98) | 276 (14.18) | 160 (25.76) | <0.001 | | Vasopressor use | | | | | | No vasopressor | 1,765 (68.76) | 1,442 (74.10) | 323 (52.01) | <0.001 | | One vasopressor | 512 (19.95) | 338 (17.37) | 174 (28.02) | | Two vasopressors | 290 (11.30) | 166 (8.53) | 124 (19.97) | | Antibiotics use | 2,208 (86.01) | 1,677 (86.18) | 531 (85.51) | 0.308 |
|