Efficacy and safety of corticosteroids in immunocompetent patients with septic shock
Xin Lu1, Wei Han2, Yan-xia Gao3, Shi-gong Guo4, Shi-yuan Yu1, Xue-zhong Yu1, Hua-dong Zhu1, Yi Li1(
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Figure 3.. Trial sequential analysis of all trials for short-term mortality. TSA: trial sequential analysis. The required information size was 1,671 patients. The incidence in the control arm of 45.1% with a relative risk reduction of 15.0% produced an incidence of 38.3% in the corticosteroid group. The TSA-adjusted 95% confidence interval for a relative risk of 0.95 was 0.83 to 1.09 and the cumulative Z-curves crossed futility area.
