Predictive value of neutrophil-to-lymphocyte ratio and other inflammatory indicators in estimating clinical severity of coronavirus disease

Guang-qing Yu, Qing Zhang, Run-chang Wang, Shi-qin Jiang

Table 1 Pooled outcomes of blood parameters in severe COVID-19

Indicators Number of studies reporting variables Number of patients analyzed Pooled WMD with 95% CI I2 P-value WBC[2-4,6-9] 7 1,514 1.48×109/L (0.90-2.05) 65.1% <0.001 Neutrophil[2-4,6-9] 7 1,514 1.80×109/L (1.25-2.35) 61.4% <0.001 Lymphocyte[2-4,6-9] 7 1,514 -0.35×109/L (-0.48 to -0.22) 81.7% <0.001 Monocyte[2,4,6] 3 661 0.00×109/L (-0.02 to 0.03) 0.0% 0.731 Platelet[3,6,8,9] 4 894 -26.39×109/L (-46.50 to -6.27) 66.1% <0.010 CRP[2,4,5,7-10] 7 1,539 41.23 mg/L (28.86-53.60) 72.2% <0.001