Factors associated with refractory pain in emergency patients admitted to emergency general surgery
William Gilliam, Jackson F. Barr, Brandon Bruns, Brandon Cave, Jordan Mitchell, Tina Nguyen, Jamie Palmer, Mark Rose, Safura Tanveer, Chris Yum, Quincy K. Tran
Table 3 Comparison of ED interventions for patients with and without refractory pain
Parameters All
(n=200)
No refractory pain
(group A)
(n=142)
Refractory pain
(group B)
(n=58)
P-value
(A vs. B)
Number of pain medication administration, median (IQR) 4 (3-6) 4 (3-7) 3 (3-5) 0.001
Pain medication type, n (%)*
No pain medication 26 (13) 13 (9) 13 (22) 0.020
Any opioids 164 (82) 123 (87) 41 (70) 0.010
Opioids+non-opioids 20 (10) 14 (10) 6 (10) 0.890
Non-opioids 30 (15) 20 (14) 10 (17) 0.730
Total MEU, mean±SD 22±11 13±9 9±16 0.020
MEU per kg (body weight), mean±SD 0.15±0.16 0.18±0.20 0.11±0.10 0.004
Total intravenous crystalloids (liter), mean±SD 1.4±1.0 1.2±0.9 1.8±1.2 0.017
IVF per kg, mean±SD 17±1 16±14 21±17 0.060
Any anti-emetics, n (%) 134 (67) 97 (68) 37 (64) 0.650
Total number of antibiotics, median (IQR) 0 (0-1) 0 (0-1) 1 (0-2) 0.038
Receiving any antibiotics, n (%) 92 (46) 60 (42) 32 (55) 0.130